Wound healing is a complex biological process that repairs damaged tissues and restores skin integrity. Insulin, a potent factor of wound healing, has been reported for nearly a century to induce rapid recovery of various wounds, as shown by numerous human and animal studies.
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The failure in timely healing of wounds is a central feature in chronic wounds that leads to physiological, psychological and economic burdens. Macrophages have been demonstrated to have various functions in wounds including host defense, the promotion and resolution of inflammation, the removal of apoptotic cells and tissue restoration following injury.
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MolecuLight Inc., the world’s leader in handheld fluorescence imaging for real-time detection of bacteria in wounds, announces the publication of “In vitro detection of porphyrin-producing wound bacteria with real-time fluorescence imaging” in Future Microbiology.
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A combined literature review and retrospective study has confirmed that the use of a dermal regenerative template is “a viable option for providing vascularised coverage over wounds with avascular components”. Moreover, it was also found by Ronald N Bogdasarian (Rutgers New Jersey Medical School, Newark, USA) and colleagues that DRT is less successful in chronic wounds.
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Neisseria animaloris is a rare pathogen in humans primarily associated with dog and cat bites. Fourteen cases have been documented in the literature related to the difficulty in identifying this bacterium in the laboratory. We present a patient case demonstrating a prolonged treatment course, which is often seen as the result of misdiagnosis, and subsequent nonhealing wound requiring multiple surgeries and eventual wide excision with staged graft coverage.
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OBJECTIVE: To study the epidemiology and characteristics of wounds related to malignancy in a large, academically affiliated postacute/long-term care facility.
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Researchers at Indiana University have discovered that a chemical compound found in essential oils can improve wound healing when applied topically on mice. The compound beta-caryophyllene can be found in essential oils such as lavender.
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Key to collective cell migration is the ability of cells to rearrange their position with respect to their neighbors. Recent theory and experiments demonstrate that cellular rearrangements are facilitated by cell shape, with cells having more elongated shapes and greater perimeters more easily sliding past their neighbors within the cell layer.
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Smith+Nephew, the global medical technology business, is excited to announce the publication of results from a new randomised controlled trial demonstrating that the use of PICO◊ Single Use Negative Pressure Wound Therapy System significantly reduced wound area, depth and volume compared with traditional negative pressure wound therapy in patients with venous leg ulcers and diabetic foot ulcers.
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Beta-caryophyllene is an odoriferous bicyclic sesquiterpene found in various herbs and spices. Recently, it was found that beta-caryophyllene is a ligand of the cannabinoid receptor 2 (CB2). Activation of CB2 will decrease pain, a major signal for inflammatory responses.
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